Libyan Journal of Medical Sciences

SHORT COMMUNICATION
Year
: 2017  |  Volume : 1  |  Issue : 3  |  Page : 80--82

Molecular investigation of carbapenemase-producing enterobacteriaceae isolated from a Tripoli Hospital, Libya


Mohamed O Ahmed1, Ezzeddin Aghila2, Samira Elamri2, Keith E Baptiste3 
1 Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
2 Burns and Plastic Surgery Centre, Tripoli, Libya
3 Department of Veterinary Medicine, Danish Medicines Agency, Copenhagen, Denmark

Correspondence Address:
Dr. Mohamed O Ahmed
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, P.O. Box 13662, University of Tripoli, Tripoli
Libya

Background: Carbapenemase producing bacteria are a serious public health concern and further pressure on the last-resort antimicrobials. Objectives: The aim of the study was to investigate the molecular characteristics of 48 multi-resistant Enterobacteriaceae isolates recovered from clinical samples. Materials and Methods: Isolates were investigated by antimicrobial susceptibility testing and polymerase chain reaction protocols for blaOXA-48and metallo-beta-lactamase genes. Results: Klebsiella pneumoniae and Escherichia coli isolates demonstrated high frequencies of multidrug resistance and various phenotypes. Eleven K. pneumoniae carried extended-spectrum β-lactamases genes of which four strains possessed both OXA-48 and New Delhi metallo genes. Conclusion: Carbapenemase-producing bacteria in the Libyan health system warrants further attention and are possibly underestimated. Urgent control and prevention actions are required.


How to cite this article:
Ahmed MO, Aghila E, Elamri S, Baptiste KE. Molecular investigation of carbapenemase-producing enterobacteriaceae isolated from a Tripoli Hospital, Libya.Libyan J Med Sci 2017;1:80-82


How to cite this URL:
Ahmed MO, Aghila E, Elamri S, Baptiste KE. Molecular investigation of carbapenemase-producing enterobacteriaceae isolated from a Tripoli Hospital, Libya. Libyan J Med Sci [serial online] 2017 [cited 2022 Nov 29 ];1:80-82
Available from: https://www.ljmsonline.com/article.asp?issn=2588-9044;year=2017;volume=1;issue=3;spage=80;epage=82;aulast=Ahmed;type=0