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Year : 2018  |  Volume : 2  |  Issue : 2  |  Page : 73-76

Severe cholestasis with marked weight loss mimicking malignancy: An overlooked etiology

1 Department of Medicine, Hamad General Hospital, Qatar University and Weill Cornell Medical College, Doha, Qatar
2 Department of Medicine, Weill Cornel Medical College, Doha, Qatar
3 Department of Medicine, Hamad General Hospital and Weill Cornell Medical College, Doha, Qatar

Correspondence Address:
Prof. Wanis H Ibrahim
Department of Medicine, Hamad General Hospital, College of Medicine, Qatar University and Weill Cornell Medical College, Doha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/LJMS.LJMS_10_18

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Despite being classified as controlled substances in many countries, the use of anabolic androgenic steroids is becoming widespread and no longer limited to bodybuilders or elite athletes. A plausible reason that has fuelled increasing use of such drugs is the increase in modern perception of "ideal" body image and the desire to increase masculinity among younger people. Such drugs are illegally sold through the black market, websites, gyms, body building competitions, teammates, trainers, etc. the health consequences of these medications including their hepatotoxicity are often overlooked. Anabolic androgenic steroid-induced cholestasis may exhibit symptoms and signs indistinguishable from malignancy-induced cholestasis. Patients tend to deny or withhold information regarding the use of these medications. Specific and direct inquiry about the use of these drugs is imperative particularly in young men presenting with cholestatic jaundice. In this paper, we report a 40-year old man with severe cholestasis and marked weight loss (mimicking malignancy) secondary to anabolic androgenic steroid use for bodybuilding. We also performed extensive literature search regarding cholestasis as well other health consequences caused by these medications.

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