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Year : 2017  |  Volume : 1  |  Issue : 3  |  Page : 80-82

Molecular investigation of carbapenemase-producing enterobacteriaceae isolated from a Tripoli Hospital, Libya

1 Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
2 Burns and Plastic Surgery Centre, Tripoli, Libya
3 Department of Veterinary Medicine, Danish Medicines Agency, Copenhagen, Denmark

Correspondence Address:
Dr. Mohamed O Ahmed
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, P.O. Box 13662, University of Tripoli, Tripoli
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/LJMS.LJMS_24_17

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Background: Carbapenemase producing bacteria are a serious public health concern and further pressure on the last-resort antimicrobials. Objectives: The aim of the study was to investigate the molecular characteristics of 48 multi-resistant Enterobacteriaceae isolates recovered from clinical samples. Materials and Methods: Isolates were investigated by antimicrobial susceptibility testing and polymerase chain reaction protocols for blaOXA-48and metallo-beta-lactamase genes. Results: Klebsiella pneumoniae and Escherichia coli isolates demonstrated high frequencies of multidrug resistance and various phenotypes. Eleven K. pneumoniae carried extended-spectrum β-lactamases genes of which four strains possessed both OXA-48 and New Delhi metallo genes. Conclusion: Carbapenemase-producing bacteria in the Libyan health system warrants further attention and are possibly underestimated. Urgent control and prevention actions are required.

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