| SHORT COMMUNICATION |
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| Year : 2017 | Volume
: 1
| Issue : 3 | Page : 80-82 |
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Molecular investigation of carbapenemase-producing enterobacteriaceae isolated from a Tripoli Hospital, Libya
Mohamed O Ahmed1, Ezzeddin Aghila2, Samira Elamri2, Keith E Baptiste3
1 Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya
2 Burns and Plastic Surgery Centre, Tripoli, Libya
3 Department of Veterinary Medicine, Danish Medicines Agency, Copenhagen, Denmark
Correspondence Address:
Dr. Mohamed O Ahmed
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, P.O. Box 13662, University of Tripoli, Tripoli
Libya
 Source of Support: None, Conflict of Interest: None  | 10 |
DOI: 10.4103/LJMS.LJMS_24_17
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Background: Carbapenemase producing bacteria are a serious public health concern and further pressure on the last-resort antimicrobials. Objectives: The aim of the study was to investigate the molecular characteristics of 48 multi-resistant Enterobacteriaceae isolates recovered from clinical samples. Materials and Methods: Isolates were investigated by antimicrobial susceptibility testing and polymerase chain reaction protocols for blaOXA-48and metallo-beta-lactamase genes. Results: Klebsiella pneumoniae and Escherichia coli isolates demonstrated high frequencies of multidrug resistance and various phenotypes. Eleven K. pneumoniae carried extended-spectrum β-lactamases genes of which four strains possessed both OXA-48 and New Delhi metallo genes. Conclusion: Carbapenemase-producing bacteria in the Libyan health system warrants further attention and are possibly underestimated. Urgent control and prevention actions are required. |
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