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Year : 2017  |  Volume : 1  |  Issue : 1  |  Page : 18-20

Rhabdomyolysis and acute renal failure associated with pneumococcal meningitis: A case report and literature review

Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Weill Cornell Medical College, Doha, Qatar

Correspondence Address:
Fahmi Yousef Khan
Department of Medicine, Hamad General Hospital, P. O. Box 3050, Doha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/LJMS.LJMS_5_17

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We report a case of acute pneumococcal meningitis complicated by rhabdomyolysis and acute renal failure in a 46-year-old Indian man who was brought to the emergency department in an unconscious state after a witnessed generalized tonic–clonic seizure that resolved spontaneously. Lumbar puncture was performed, and cerebrospinal fluid (CSF) analysis revealed white blood cell count of 1500 cells/mm3 (98% neutrophils); glucose level <0.1 mmol/L; and protein level 5.57 g/L. Blood chemistry showed high serum creatinine and creatine phosphokinase (CPK). The patient was sent to the Intensive Care Unit, where he received intravenous antibiotic with early and aggressive hydration, while CSF culture was pending. Two days later, the CSF culture yielded Streptococcus pneumoniae which was sensitive to ceftriaxone and penicillin G. Therefore, ceftriaxone continued for a total of 14 days. The patient maintained good urine output throughout the illness, and his renal parameters improved without dialysis. Eighteen days after admission, he was discharged without fever and with a normal renal function and normal creatine kinase level.

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